Drug cuts bleeding risk in kidney stone surgery

NCT ID NCT07582341

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving tranexamic acid, a drug that helps blood clot, through a vein and in surgical fluid can reduce bleeding during kidney stone removal. 90 adults with large kidney stones were randomly assigned to receive the drug or a placebo. The goal was to see if it lowers blood loss, improves the surgeon's view, and reduces the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If it works, this could make kidney stone surgery safer by reducing blood loss and the need for blood transfusions.
What could go wrong
This is a small, single-center study with 90 participants. Results may not apply to all patients, and tranexamic acid can rarely cause allergic reactions or blood clots.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical Hemorrhage Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha University Hospital

    Banhā, Qalyubia Governorate, 13511, Egypt

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