Heart surgery bleeding study tests best drug dose

NCT ID NCT07164300

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study compares three different doses of the drug tranexamic acid in 150 adults having elective heart surgery with a heart-lung machine. The goal is to find which dose best controls bleeding and reduces the need for blood transfusions. Researchers will measure how long the drug works and its levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If successful, this study could help doctors choose the best dose of tranexamic acid to reduce bleeding and transfusions during heart surgery.
What could go wrong
This is a small, early-phase trial with 150 participants. Different doses may not show clear benefits, and individual patient responses can vary.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease Drug-Related Side Effects and Adverse Reactions Hemorrhage Postoperative Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital of Ioannina

    RECRUITING

    Ioannina, Greece

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