New study tracks COVID-19 vaccine side effects in kids ages 5 to 16

NCT ID NCT05157191

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study follows children and adolescents aged 5 to 16 who receive an mRNA COVID-19 vaccine to monitor for side effects like injection site pain, fever, and other reactions. Participants report symptoms for a week after each dose, and some provide blood samples to measure antibody levels. The goal is to better understand the safety and immune response of COVID-19 vaccines in younger populations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mRNA COVID-19 vaccine

What this could lead to

If successful, this study could provide clear safety data on COVID-19 vaccines in children, helping guide vaccination recommendations.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all children or vaccine types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Drug-Related Side Effects and Adverse Reactions Injection Site Reaction Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centers for Disease Control and Prevention

    Atlanta, Georgia, 30333, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Columbia University

    New York, New York, 10027, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Kaiser Permanente Northern California

    Oakland, California, 94612, United States