Could a simple drug make nose jobs safer and less bruising?

NCT ID NCT05774717

First seen May 14, 2026 · Last updated Jun 19, 2026 · Updated 7 times

Summary

This study tests whether a single dose of tranexamic acid (TXA), given just before nose surgery, can reduce bleeding during the operation and lessen bruising and swelling afterward. Sixty adults having cosmetic or functional rhinoplasty will be randomly assigned to receive TXA or a placebo. The goal is to see if this common drug can improve recovery without causing serious side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tranexamic acid (TXA)

What this could lead to

If it works, this could give surgeons a simple way to reduce bleeding, bruising, and swelling after nose surgery, helping patients recover more comfortably.

What could go wrong

This is a small, early-phase trial with only 60 people, so results may not apply to everyone. TXA also carries rare risks like blood clots or allergic reactions.

Conditions

The condition(s) this trial relates to.

Postoperative Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.