Targeted drug shows promise for rare BRAF cancers
NCT ID NCT04439279
First seen Nov 19, 2025 · Last updated Jun 16, 2026 · Updated 27 times
Summary
This study tests the drug trametinib in 35 adults with advanced cancers that have certain BRAF gene mutations or fusions. Trametinib blocks proteins that help cancer cells grow. The goal is to see if the drug can shrink tumors or stop them from growing. Participants must have already been enrolled in the main MATCH study and meet specific heart health criteria.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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ECOG-ACRIN Cancer Research Group
Philadelphia, Pennsylvania, 19103, United States
Conditions
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