Targeted drug shows promise for rare BRAF-altered tumors
NCT ID NCT04439279
First seen Nov 19, 2025 · Last updated Apr 28, 2026 · Updated 17 times
Summary
This study tests the drug trametinib in people with advanced cancers that have specific BRAF gene changes (mutations or fusions). Trametinib blocks certain proteins that help cancer cells grow. The goal is to see if the drug can shrink tumors or stop them from growing. The study includes 35 adults with solid tumors, lymphoma, or multiple myeloma that have not responded to other treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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ECOG-ACRIN Cancer Research Group
Philadelphia, Pennsylvania, 19103, United States
Conditions
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