New drug combo shows promise for Tough-to-Treat melanoma

NCT ID NCT03501368

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 32 times

Summary

This early-phase study tested a combination of two drugs, trametinib and ceritinib, in 27 people with advanced melanoma that had stopped responding to standard treatments. The main goal was to find the safest dose and see if the combination could shrink tumors. While not a cure, the approach aims to control the disease in patients with few remaining options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.