Could a simple additive to a nerve block ease pain after prostate surgery?

NCT ID NCT07289321

ENROLLING_BY_INVITATION Symptom relief Sponsor: Aretaieion University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding tramadol or magnesium to a standard local anesthetic (ropivacaine) for a nerve block can better control pain during and after robotic prostate removal. Ninety men aged 40-80 will be randomly assigned to receive one of three solutions: ropivacaine alone, ropivacaine plus tramadol, or ropivacaine plus magnesium. Researchers will measure pain levels and painkiller use in the first 24 hours and follow up at 3 and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tramadol and magnesium added to ropivacaine for a nerve block
What this could lead to: If it works, this could lead to better pain control after robotic prostate surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage study with only 90 participants. The added drugs may not improve pain relief or could cause side effects like nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIOPERATIVE PAIN IN ROBOTIC PROSTATECTOMY

Contacts and locations

Locations

Aretaieion University Hospital of Athens

Athens, Attica, 11528, Greece

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