Could a simple additive to a nerve block ease pain after prostate surgery?

NCT ID NCT07289321

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding tramadol or magnesium to a standard local anesthetic (ropivacaine) for a nerve block can better control pain during and after robotic prostate removal. Ninety men aged 40-80 will be randomly assigned to receive one of three solutions: ropivacaine alone, ropivacaine plus tramadol, or ropivacaine plus magnesium. Researchers will measure pain levels and painkiller use in the first 24 hours and follow up at 3 and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tramadol and magnesium added to ropivacaine for a nerve block

What this could lead to

If it works, this could lead to better pain control after robotic prostate surgery, reducing the need for strong painkillers.

What could go wrong

This is a small, early-stage study with only 90 participants. The added drugs may not improve pain relief or could cause side effects like nausea.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aretaieion University Hospital of Athens

    Athens, Attica, 11528, Greece