First human trial tests new weapon against multiple cancers
NCT ID NCT04344795
Summary
This early-stage study aimed to find a safe and effective dose of a new drug called TPST-1495, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced solid tumors. It enrolled 89 adults with cancers like colorectal, lung, and head and neck cancer who had run out of standard treatment options. The main goal was to understand the drug's safety, how the body processes it, and to see early signs of whether it might help shrink tumors.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baystate Gynecologic Oncology
Springfield, Massachusetts, 01107, United States
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Carolina BioOncology Institute
Huntersville, North Carolina, 28078, United States
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SCRI-OK Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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START Midwest
Grand Rapids, Michigan, 49546, United States
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Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
Baltimore, Maryland, 21287, United States
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South Texas Accelerated Research Therapeutics (START)
San Antonio, Texas, 78229, United States
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Tennessee Oncology
Nashville, Tennessee, 37203, United States
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University of Colorado
Aurora, Colorado, 80045, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of Pennsylvania Perelman School of Medicine
Philadelphia, Pennsylvania, 19104, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Conditions
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