New hope for kids with tough brain tumors: experimental drug shows promise
NCT ID NCT03429803
First seen Feb 23, 2026 · Last updated Apr 28, 2026 · Updated 7 times
Summary
This study tested a drug called Tovorafenib in 44 children and young adults with low-grade gliomas (a type of brain tumor) that had come back or grown despite other treatments. The main goal was to find the safest dose and check for side effects. The drug works by blocking a specific pathway that helps these tumors grow.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Minnesota
Minneapolis, Minnesota, 55404, United States
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Children's National Hospital
Washington D.C., District of Columbia, 20010, United States
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Dana-Farber Cancer Institite
Boston, Massachusetts, 02215, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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Massacusetts General Hospital
Boston, Massachusetts, 02114, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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University of California, San Diego
San Diego, California, 92123, United States
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University of California, San Francisco
San Francisco, California, 94158, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Utah
Salt Lake City, Utah, 84113, United States
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Washington University in St. Louis
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.