Gene study aims to personalize lung cancer chemotherapy
NCT ID NCT07145333
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how genetic differences (SNPs) in drug targets influence how well topotecan works and its side effects in 600 people with small cell lung cancer. Participants are randomly assigned to receive either the usual topotecan capsule or an imported version. Researchers will sequence specific genes to find links between genetics and treatment outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Topotecan
What this could lead to
If successful, this could help doctors predict which patients will benefit most from topotecan and who might have severe side effects, leading to more personalized treatment.
What could go wrong
This is an observational genetic analysis, not a test of a new treatment. The findings may not change current practice and require further validation.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medicine Invention Design Incorporation
Rockville, Maryland, 20853, United States