Could a scalp gel save your hair during chemo? early trial begins

NCT ID NCT07033845

Recruiting now Symptom relief Sponsor: Applied Biology, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a topical phenylephrine gel applied daily to the scalp for three weeks. Researchers want to see how much of the drug enters the bloodstream and whether it is safe. The study involves 24 healthy women aged 18-55, not cancer patients, so it is a first step toward possibly preventing chemotherapy-induced hair loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Phenylephrine (topical solution applied to scalp)
What this could lead to: If it works, this could point toward a way to reduce hair loss during chemotherapy.
What could go wrong: This is a very early, small study in healthy women, not patients. It only checks safety and absorption, not whether it actually prevents hair loss. Side effects like skin irritation or blood pressure changes are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced alopecia chemotherapy-induced toxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEMOTHERAPY SIDE EFFECTS CHEMOTHERAPY-INDUCED ALOPECIA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

University of Rome ("G. Marconi")
RECRUITING

Rome, Italy

Contact Email: •••••@•••••

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