Smartwatch-Like device could help test DMD drugs in toddlers

NCT ID NCT07423026

Recruiting now Knowledge-focused Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a watch-like device worn on the ankle can measure how well toddlers with Duchenne muscular dystrophy (DMD) move during their daily activities. Researchers will ask 30 boys with DMD and 30 without (ages 1-3) to wear the device for three 28-day periods over six months. The goal is to see if the device is comfortable, reliable, and can detect changes in walking ability, which could help test new medicines in younger children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Syde wearable device (ankle-worn activity monitor)
What this could lead to: If successful, this could provide a way to test new DMD medicines in very young children, potentially speeding up development of treatments.
What could go wrong: This is a small, early-stage feasibility study (60 boys) focused on measurement, not treatment. The device may not work well in toddlers or may not detect meaningful changes.

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Conditions

The condition(s) this trial relates to.

Duchenne muscular dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DUCHENNE MUSCULAR DYSTROPHY (DMD)

Contacts and locations

Locations

Oxford University
RECRUITING

Oxford, United Kingdom

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