Blood test may predict chemo failure in aggressive breast cancer

NCT ID NCT04771871

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how well standard chemotherapy works in people with triple-negative breast cancer, an aggressive type that lacks targeted treatments. Researchers will also measure tiny molecules called microRNAs and tumor DNA in the blood to see if changes can signal when the drugs stop working. The goal is to find a simple blood test that helps doctors adjust treatment early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Epirubicin, Cyclophosphamide, Paclitaxel, Carboplatin (chemotherapy drugs)

What this could lead to

If successful, this could lead to a simple blood test that tells doctors early when chemotherapy is not working, allowing them to switch treatments sooner.

What could go wrong

This is a small, early-phase study with only 42 people. The blood test idea is still experimental and may not prove reliable enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm Neoplastic Cells, Circulating triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lagos State University Teaching Hospital

    NOT_YET_RECRUITING

    Lagos, Nigeria

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lagos University Teaching Hospital

    NOT_YET_RECRUITING

    Lagos, Nigeria

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Obafemi Awolowo University Teaching Hospital

    NOT_YET_RECRUITING

    Ile-Ife, Oshun, Nigeria

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University College Hospital

    RECRUITING

    Ibadan, Oyo State, 200221, Nigeria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••