Can brain zaps and cash rewards break Cocaine's grip?
NCT ID NCT07490600
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a combination of two treatments for people with cocaine use disorder: deep transcranial magnetic stimulation (TMS), which uses magnetic pulses to stimulate the brain, and contingency management, a program that rewards participants for staying cocaine-free. The goal is to see if this combo helps people stop using cocaine and reduces cravings. The study involves 100 participants who will attend clinic visits three times a week.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- deep transcranial magnetic stimulation (TMS) plus contingency management (a reward program for staying cocaine-free)
- What this could lead to
- If it works, this could offer a new treatment option for people with cocaine use disorder who don't respond to standard approaches.
- What could go wrong
- This is an early-stage study with only 100 participants, so results may not apply to everyone. The treatment is intensive (three clinic visits per week) and may not work for all individuals.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The University of Texas Health Science Center at Houston
RECRUITINGHouston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.