Memory boost for cocaine users? small study tests potassium channel blocker
NCT ID NCT07532460
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a drug called fampridine, which blocks potassium channels in the brain, can improve working memory in people with cocaine use disorder. Forty chronic cocaine users will receive either the drug or a placebo and then take memory tests. The goal is to understand the brain mechanisms behind cognitive problems in cocaine users, not to test a cure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fampridine (4-aminopyridine)
- What this could lead to
- If it works, this could point toward a treatment for cognitive impairments in people with cocaine use disorder.
- What could go wrong
- This is a very small, early-stage study with only 40 participants. It tests a single dose, so any effects may be temporary or not translate to real-world benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital of Psychiatry Zurich
Zurich, Canton of Zurich, 8008, Switzerland
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