New study tests faster brain zaps for stubborn depression

NCT ID NCT07264452

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two accelerated forms of transcranial magnetic stimulation (TMS) for people with treatment-resistant depression. 60 participants will receive either intermittent or continuous theta burst stimulation over two weeks, with a 12-week follow-up. The goal is to see which type better reduces depression, anxiety, and suicidal thoughts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS) using a figure-eight coil
What this could lead to
If successful, this could identify a more effective TMS protocol for people with depression that hasn't responded to medication.
What could go wrong
This is a small, early-stage study with only 60 participants. The results may not apply to everyone, and the benefits might not last beyond the 12-week follow-up.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ataturk University

    RECRUITING

    Erzurum, 25240, Turkey (Türkiye)

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