Brain zaps for sound rage: TMS tested for misophonia
NCT ID NCT06960083
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study tests whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique already used for depression, can help people with misophonia tolerate trigger sounds. Sixty adults will each receive two TMS sessions (one inhibitory, one excitatory) targeting the parietal region. Before and after stimulation, they will rate how unpleasant sounds are while their brain activity, heart rate, and skin temperature are measured.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Transcranial Magnetic Stimulation (TMS)
- What this could lead to
- If it works, this could point toward a non-invasive brain stimulation treatment to reduce the distress caused by misophonia triggers.
- What could go wrong
- This is a very early, small study with only two sessions of TMS. It may not produce lasting or meaningful symptom relief, and results may not apply to everyone with misophonia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mount Sinai West
RECRUITINGNew York, New York, 10022, United States
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