Can a precise dose of brain zaps boost memory and mood in seniors?

NCT ID NCT05992831

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find the best dose of a safe, non-invasive brain stimulation technique called accelerated TMS to improve both depression and thinking skills in people aged 60-85 with mild cognitive impairment and depression. About 60 participants will receive different doses of TMS, and researchers will measure changes in mood and cognitive function. The goal is to gather data needed to design larger trials that could eventually help prevent dementia.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••