Tiny study on nerve surgery for amputees halted early
NCT ID NCT04658368
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to measure how targeted muscle reinnervation (TMR) surgery affects quality of life and function in people who have had a major limb amputation. TMR was done either at the time of amputation or later. Only 2 people took part before the study was stopped early, so the findings are very limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Targeted muscle reinnervation (TMR) surgery
- What this could lead to
- If successful, this could show that TMR improves quality of life and function for people with major limb amputations.
- What could go wrong
- The study was terminated early with only 2 participants, so results are very limited and may not apply to others. It was also a small, single-center study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Wisconsin
Madison, Wisconsin, 53792, United States
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