Jaw pain showdown: which injection works best?

NCT ID NCT07571265

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested three different injections for people with painful jaw arthritis: platelet-rich plasma (PRP), hyaluronic acid, and a steroid called triamcinolone acetonide. 64 adults received one of these or a placebo saline injection. Researchers measured pain and mouth opening after one week, one month, and three months to see which treatment worked best.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
platelet-rich plasma, hyaluronic acid, triamcinolone acetonide
What this could lead to
If one injection works best, it could offer a simple, non-surgical option for easing jaw arthritis pain.
What could go wrong
This is a small, single-center study with only 64 participants. Results may not apply to everyone, and any injection carries risks like infection or temporary discomfort.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry

    Al Manyal, Cairo Governorate, 11553, Egypt

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