Weight-Loss drug may slow uterine tumors before surgery

NCT ID NCT07078838

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 16 times

Summary

This study tests whether tirzepatide, a drug used for diabetes and weight loss, can slow or stop the growth of early-stage endometrial cancer or its precursor (EIN) in women with obesity. Forty participants will either receive tirzepatide or standard care for 4 weeks before their scheduled hysterectomy. Researchers will compare tissue samples to see if the drug reduces cell growth in the uterus.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

Conditions

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