New drug combo aims to fight tough childhood cancer

NCT ID NCT06540963

Recruiting now Disease control Sponsor: Giselle Sholler Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new pill called tipifarnib combined with an FDA-approved drug, naxitamab, for people with neuroblastoma that has come back or not responded to treatment. The goal is to see if the combination is safe and helps shrink tumors or slow the disease. The trial is for patients aged 1 to 21 years at diagnosis, with about 98 participants expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEUROBLASTOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROBLASTOMA

Contacts and locations

Locations

Arkansas Children's Hospital
RECRUITING

Little Rock, Arkansas, 72202, United States
Arnold Palmer Hospital for Children
RECRUITING

Orlando, Florida, 32806, United States
Cardinal Glennon Children's Medical Center
RECRUITING

St Louis, Missouri, 63104, United States
Children's Medical Center
RECRUITING

Dallas, Texas, 75235, United States
Connecticut Children's Hospital
RECRUITING

Hartford, Connecticut, 06106, United States
Dell Children's Blood and Cancer Center
RECRUITING

Austin, Texas, 78723, United States
Duke University
RECRUITING

Durham, North Carolina, 27708, United States
Kapiolani Medical Center for Women and Children
RECRUITING

Honolulu, Hawaii, 96813, United States
Monroe Carrell Jr. Children's Hospital at Vanderbilt
RECRUITING

Nashville, Tennessee, 37232, United States
Nicklaus Children's Hospital
RECRUITING

Miami, Florida, 33155, United States
Penn State Milton S. Hershey Medical Center and Children's Hospital
RECRUITING

Hershey, Pennsylvania, 17033, United States
Randall Children's Hospital
RECRUITING

Portland, Oregon, 97227, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.