New hope for nail psoriasis: drug shows promise in phase 3 trial

NCT ID NCT03897075

First seen Apr 12, 2026 · Last updated May 06, 2026 · Updated 4 times

Summary

This study tested a drug called tildrakizumab in 99 adults with moderate to severe nail psoriasis, a condition causing nail damage and pain. Participants received either the drug or a placebo for 28 weeks to see if it improved nail appearance and symptoms. The goal was to find a safe, effective treatment for this hard-to-treat form of psoriasis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • California Dermatology & CRI (Site 18)

    Encinitas, California, 92007, United States

  • Center for Clinical Studies (Site 11)

    Houston, Texas, 77004, United States

  • Center for Clinical Studies Cypress (Site 17)

    Cypress, Texas, 77433, United States

  • Clinical Partners, LLC (Site 08)

    Johnston, Rhode Island, 02919, United States

  • Clinical Science Institute (Site 14)

    Santa Monica, California, 90404, United States

  • Dermatology Research Associates (Site 09)

    Los Angeles, California, 90045, United States

  • First OC Dermatology (Site 07)

    Fountain Valley, California, 92708, United States

  • Florida Academic Centers Research and Education, LLC (Site 21)

    Coral Gables, Florida, 33134, United States

  • Forest Hills Dermatology Group (Site 04)

    Forest Hills, New York, 11375, United States

  • Fremantle Dermatology (Site 40)

    Fremantle, WAUS, 6160, Australia

  • North Eastern Health Specialists (Site 46)

    Campbelltown, South Australia, 5073, Australia

  • Premier Dermatology (Site 47)

    Kogarah, New South Wales, 2217, Australia

  • Progressive Clinical Research (Site 27)

    San Antonio, Texas, 78213, United States

  • Renstar Medical Research (Site 23)

    Ocala, Florida, 34470, United States

  • Skin Health Institute Inc. (Site 43)

    Carlton, Victoria, 3053, Australia

  • St George Dermatology & Skin Cancer Centre (Site 45)

    Kogarah, New South Wales, 2217, Australia

  • Veracity Clinical Research/ Specialist Connect(Site 44)

    Woolloongabba, QSLD, 4102, Australia

Conditions

Explore the condition pages connected to this study.