New drug trial aims to boost power of standard thyroid cancer treatment

NCT ID NCT05783323

First seen Nov 16, 2025 · Last updated Apr 23, 2026 · Updated 24 times

Summary

This study is testing whether a drug called larotrectinib can make radioactive iodine therapy more effective for people with advanced thyroid cancer that has spread to the lungs. The goal is to see if taking larotrectinib before standard radioactive iodine treatment helps shrink lung tumors more completely. The trial is for patients aged 1 and older whose cancer has a specific genetic change called an NTRK fusion.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 19807, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94115, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.