Sound waves to zap hypertension? new trial tests ultrasound treatment
NCT ID NCT06559891
First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 4 times
Summary
This study tests a device that uses ultrasound to calm overactive nerves in the kidneys, which can drive high blood pressure. About 261 adults with hypertension will either get the real procedure or a sham (fake) one. The goal is to see if this approach safely lowers blood pressure, possibly reducing the need for daily medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ultrasound energy delivered via a catheter to nerves around the kidney arteries
What this could lead to
If it works, this could offer a new, drug-free option to help control high blood pressure without daily pills.
What could go wrong
This is an early-stage device trial with only 261 participants. The procedure involves risks like blood vessel damage, and it may not lower blood pressure enough to replace medication.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Arkansas Heart Hospital
RECRUITINGLittle Rock, Arkansas, 72211, United States
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Ascension Alexian Brothers
RECRUITINGElk Grove Village, Illinois, 60007, United States
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Ascension St. John Clinical Research Institute
RECRUITINGBartlesville, Oklahoma, 74006, United States
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Ascension- Sacred Heart
RECRUITINGPensecola, Florida, 32504, United States
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Athens Hippokration
RECRUITINGAthens, Greece
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Bridgeport
RECRUITINGBridgeport, Connecticut, 06610, United States
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Cardiology, PC
RECRUITINGBirmingham, Alabama, 35211, United States
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Cardiovascular Institute of the South
RECRUITINGHouma, Louisiana, 70360, United States
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Cedar-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Chippenham Hospital
RECRUITINGRichmond, Virginia, 23225, United States
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Clinica Montevergine
RECRUITINGMercogliano, Italy
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Dresden TUD University of Technology
RECRUITINGDresden, Germany
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Frankfurt Sankt Katharinen Krankenhaus
RECRUITINGFrankfurt, Germany
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Freiburg Herzzenrtum
RECRUITINGFreiburg im Breisgau, Germany
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Gulfport Memorial Hospital
RECRUITINGGulfport, Mississippi, 39501, United States
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Henry Ford Hospital
RECRUITINGDetroit, Michigan, 48202, United States
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Henry Ford Providence Hospital
RECRUITINGSouthfield, Michigan, 48075, United States
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Herne Marien Hospital
RECRUITINGHerne, Germany
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Herzzentrum Leipzig
RECRUITINGLeipzig, Germany
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Honor Health Research Institue
RECRUITINGScottsdale, Arizona, 85258, United States
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Hopital Saint André
RECRUITINGBordeaux, France
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Houston Medical Center
RECRUITINGHouston, Texas, 77004, United States
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Hôpital Européen Georges-Pompidou
RECRUITINGParis, France
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Jackson Heart
RECRUITINGJackson, Mississippi, 39216, United States
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Jersey Shore University Medical Center
RECRUITINGNeptune City, New Jersey, 07753, United States
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Lancaster General Health
RECRUITINGLancaster, Pennsylvania, 17603, United States
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MUSC
RECRUITINGMt. Pleasant, South Carolina, 29464, United States
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Marienkrankenhaus Hamburg
RECRUITINGHamburg, Germany
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Medical City
RECRUITINGFort Worth, Texas, 76104, United States
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Monza Policlinico
RECRUITINGMonza, Italy
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NC Heart and Vascular
RECRUITINGRaleigh, North Carolina, 27607, United States
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Nyph/Cumc
RECRUITINGNew York, New York, 10032, United States
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Ochsner Medical Center
RECRUITINGNew Orleans, Louisiana, 70121, United States
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Ospedale Sant'Andrea
RECRUITINGRoma, Italy
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Penn Medicine
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Renown Regional Medical Center
RECRUITINGReno, Nevada, 89502, United States
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Saarland University Hospital
RECRUITINGHomburg, Germany
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Sana Kliniken Lubeck
RECRUITINGLübeck, Germany
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Southern Illinois University, School of Medicine
RECRUITINGSpringfield, Illinois, 62794, United States
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St Lukes Hospital
RECRUITINGKansas City, Missouri, 64131, United States
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St Marks Hospital
RECRUITINGSalt Lake City, Utah, 37027, United States
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St. Bernard's Medical Center
RECRUITINGJonesboro, Arkansas, 72401, United States
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St. John's Prairie Heart
RECRUITINGSpringfield, Illinois, 62710, United States
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St. Joseph
RECRUITINGLiverpool, New York, 13088, United States
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Stanford University
RECRUITINGPalo Alto, California, 94305, United States
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Thessaloniki Hippokration General Hospital
RECRUITINGThessaloniki, Greece
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University of Crete
RECRUITINGHeraklion, Greece
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University of South Florida
RECRUITINGTampa, Florida, 33606, United States
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Universitätsklinikum Erlangen
RECRUITINGErlangen, Germany
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Virtua Health
RECRUITINGCamden, New Jersey, 08103, United States
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