Laser zaps leg artery blockages in new trial
NCT ID NCT05916950
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new laser device called the Thor system to treat blockages in the leg arteries caused by peripheral artery disease (PAD). About 155 adults with PAD will receive the laser treatment and be followed for a year. The main goals are to see if the device is safe and if it successfully opens the blocked arteries.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Thor laser atherectomy system (a device that uses laser energy to remove calcium blockages in leg arteries)
What this could lead to
If successful, this could offer a new, less invasive way to treat blocked leg arteries in people with peripheral artery disease, potentially improving blood flow and reducing symptoms.
What could go wrong
This is an early-stage study with only 155 participants, so results may not apply to everyone. Risks include artery damage, bleeding, or the blockage returning.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Ascension St. John
RECRUITINGBartlesville, Oklahoma, 74006, United States
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Atlantic Medical Imaging of New jersey
RECRUITINGVineland, New Jersey, 08360, United States
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Baylor, Scott & White, The Heart Hospital
RECRUITINGPlano, Texas, 75093, United States
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Cardiovascular Institute of the South
RECRUITINGHouma, Louisiana, 70360, United States
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Cardiovascular Institute of the South
RECRUITINGLafayette, Louisiana, 70503, United States
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Deborah Heart and Lung Center
RECRUITINGBrowns Mills, New Jersey, 08015, United States
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Guardian Research Organization
RECRUITINGWinter Park, Florida, 32792, United States
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Heart and Vascular Institute of Central Jersey
RECRUITINGNew Brunswick, New Jersey, 08901, United States
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Henry Ford Hospital
RECRUITINGDetroit, Michigan, 48202, United States
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Henry Ford St John Hospital
RECRUITINGDetroit, Michigan, 22201, United States
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Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Lankenau Institute for Medical Research
RECRUITINGWynnewood, Pennsylvania, 19096, United States
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Manatee Memorial Hospital
RECRUITINGBradenton, Florida, 34205, United States
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Mount Sinai Hospital
RECRUITINGNew York, New York, 10029, United States
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New York Presbyterian Hospital/Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10029, United States
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Premier Cardiovascular Institute
RECRUITINGFairborn, Ohio, 45324, United States
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Rocky Mountain Regional VA Medical Center
RECRUITINGAurora, Colorado, 80045, United States
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Sentara Health Research Center
RECRUITINGNorfolk, Virginia, 23507, United States
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Southcoast Hospitals/Charlton Memorial Hospital
RECRUITINGFall River, Massachusetts, 02720, United States
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St. Helena Hospital
RECRUITINGSt. Helena, California, 94574, United States
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Tallahassee Research Institute
RECRUITINGTallahassee, Florida, 32308, United States
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The Miriam Hospital
RECRUITINGProvidence, Rhode Island, 02905, United States
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The Vascular Care Group
RECRUITINGPortland, Maine, 04106, United States
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UPMC
RECRUITINGMechanicsburg, Pennsylvania, 17050, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Vascular Breakthroughs
RECRUITINGLeominster, Massachusetts, 04153, United States
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Vascular Institute of Chattanooga
RECRUITINGChattanooga, Tennessee, 37421, United States
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Vascular Institute of the Midwest
RECRUITINGDavenport, Iowa, 52807, United States
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Vascular Solutions of North Carolina
RECRUITINGCary, North Carolina, 27518, United States
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