New vaccine combo aims to tame chronic hepatitis b
NCT ID NCT05770895
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early-stage trial tested two experimental therapeutic vaccines, GS-2829 and GS-6779, in 83 healthy people and those with chronic hepatitis B. The main goal was to check safety and tolerability, while also measuring immune responses. The vaccines are designed to help the body fight the hepatitis B virus, potentially offering a new way to control the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GS-2829 and GS-6779 (therapeutic vaccines)
What this could lead to
If successful, this could point toward a new treatment option that helps control chronic hepatitis B without lifelong medication.
What could go wrong
This is an early Phase 1 trial focused on safety, so it is too soon to know if the vaccines will work. The study is small and may not show strong enough immune responses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 833, Taiwan
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Chang Gung Medical Foundation Linkou Chang Gung Memorial Hospital
Taoyuan City, 33305, Taiwan
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Chia-Yi Christian Hospital
Chiayi City, 60002, Taiwan
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E-DA Hospital
Kaohsiung City, 82445, Taiwan
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Kaohsiung Medical University Hospital
Kaohsiung City, 807, Taiwan
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National Cheng Kung University Hospital
Tainan, 7428, Taiwan
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National Taiwan University Hospital
Taipei, 100229, Taiwan
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New Zealand Clinical Research (NZCR)
Auckland, 1010, New Zealand
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St. Martin De Porres Hospital
Chiayi City, 600, Taiwan