Italian asthma study tracks new biologic in real life

NCT ID NCT06948396

Ongoing Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This observational study is collecting data from 315 patients in Italy who started treatment with tezepelumab for severe uncontrolled asthma. The goal is to describe their characteristics, medical history, and how their asthma exacerbation rates change over 12 to 24 months. It is not testing a new drug but gathering real-world information to better understand who benefits from this treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tezepelumab
What this could lead to: If successful, this study could provide real-world evidence on how tezepelumab works in everyday patients, potentially improving treatment guidelines for severe asthma.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by patient selection or other factors.

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Conditions

The condition(s) this trial relates to.

asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

Locations

Research Site

Cittadella (PD), Padova, Italy
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Montebelluna (TV), TV, Italy
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Aosta, Italy
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Avellino, Italy
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Bari, Italy
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Bergamo, Italy
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Brescia, Italy
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Cagliari, Italy
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Catania, Italy
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Catanzaro, Italy
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Civitanova Marche, Italy
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Ferrara, Italy
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Foggia, Italy
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Garbagnate(MI), Italy
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Genova, Italy
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Lamezia Terme, Italy
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Massa Carrara, Italy
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Milan, Italy
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Modena, Italy
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Naples, Italy
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Orbassano (TO), Italy
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Padova, Italy
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Reggio Emilia, Italy
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Roma, Italy
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Sassari, Italy
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Torino, Italy
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Tradate (VA), Italy
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Verona, Italy

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