New hope for kids with hepatitis b: drug trial shows promise

NCT ID NCT01651403

First seen Feb 01, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study tests whether the antiviral drug tenofovir can safely lower hepatitis B virus levels in children aged 2 to 12 with chronic infection. Participants receive either the drug or a placebo for 48 weeks. The goal is to see if the drug can control the virus and improve liver function, but lifelong management may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Colors Children Hospital

    Nagpur, Maharashtra, 440012, India

  • Fundeni Clinical Institute - Constantinesco

    Bucharest, 022328, Romania

  • Grigore Alexandrescu Emergency Clinical Hospital for Children

    Bucharest, 011743, Romania

  • Kyungpook National University

    Daegu, 41944, South Korea

  • M.V. Hospital and Research Centre 314/30 Mirza Mandi Chowk

    Lucknow, Uttar Pradesh, 226003, India

  • Medanta -The Medicity

    Gurgaon, Haryana, 122 001, India

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • Nirmal Hospital Private Limited

    Surat, Gujarat, 395 002, India

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Pusan National University Yangsan Hospital

    Yangsan, Gyeongsangnam-do, 50612, South Korea

  • SMS Medical College and Hospital

    Jaipur, Rajasthan, 302004, India

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Severance Children's Hospital

    Seoul, 120-752, South Korea

  • St. John Hospital & Medical Center

    Bangalore, 560034, India

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • Victor Babes Clinical Hospital of Infectious Diseases and Pneumophtisology

    Craiova, 200515, Romania

Conditions

Explore the condition pages connected to this study.