New hope for kids with hepatitis b: drug trial shows promise

NCT ID NCT01651403

Ongoing Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an antiviral drug called tenofovir in children aged 2 to 12 with chronic hepatitis B. The goal was to see if the drug could lower the amount of virus in their blood compared to a placebo. The trial involved 90 children and measured safety and effectiveness over 48 weeks.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC HEPATITIS B

Contacts and locations

Locations

Asan Medical Center

Seoul, 05505, South Korea
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Colors Children Hospital

Nagpur, Maharashtra, 440012, India
Fundeni Clinical Institute - Constantinesco

Bucharest, 022328, Romania
Grigore Alexandrescu Emergency Clinical Hospital for Children

Bucharest, 011743, Romania
Kyungpook National University

Daegu, 41944, South Korea
M.V. Hospital and Research Centre 314/30 Mirza Mandi Chowk

Lucknow, Uttar Pradesh, 226003, India
Medanta -The Medicity

Gurgaon, Haryana, 122 001, India
National Taiwan University Hospital

Taipei, 100, Taiwan
Nirmal Hospital Private Limited

Surat, Gujarat, 395 002, India
Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States
Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, 50612, South Korea
SMS Medical College and Hospital

Jaipur, Rajasthan, 302004, India
Samsung Medical Center

Seoul, 06351, South Korea
Severance Children's Hospital

Seoul, 120-752, South Korea
St. John Hospital & Medical Center

Bangalore, 560034, India
Taipei Veterans General Hospital

Taipei, 11217, Taiwan
Texas Children's Hospital

Houston, Texas, 77030, United States
University of California, San Francisco

San Francisco, California, 94143, United States
Victor Babes Clinical Hospital of Infectious Diseases and Pneumophtisology

Craiova, 200515, Romania

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