Brain tumor drug safety under scrutiny: temozolomide liver risk study launched

NCT ID NCT07675070

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study looks at how safe and effective temozolomide (brand name Amitzo) is for people with aggressive brain tumors (grade III and IV gliomas). Researchers are tracking 100 patients to see how often liver injury occurs and to monitor other side effects. The goal is to better understand the risks of this chemotherapy drug in real-world use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

temozolomide (Amitzo)

What this could lead to

If successful, this study could confirm the safety profile of temozolomide for glioma patients, potentially guiding safer treatment protocols.

What could go wrong

This is an observational study with no control group, so results may not prove cause and effect. Liver injury is a known risk of temozolomide, and the study's small size limits general conclusions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm glioblastoma glioma grade III glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Orchid Pharmed

    RECRUITING

    Tehran, Iran

    Contact Phone: •••-•••-•••• Email: •••••@•••••