New painkiller could ease recovery after bone surgery

NCT ID NCT07353996

Recruiting now Symptom relief Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a single injection of tegileridine fumarate, a new painkiller, for adults recovering from orthopedic surgeries like spinal fusion or knee replacement. Researchers aim to find the dose that works for 90% of patients without causing too many side effects. 180 participants will receive different doses to see which provides the best pain relief with the fewest problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tegileridine fumarate (a painkiller)
What this could lead to: If successful, this could establish a safe, effective single dose of tegileridine for managing pain after common orthopedic surgeries, improving recovery.
What could go wrong: This is a small, early-phase dose-finding study, not a large efficacy trial. The drug may cause side effects like nausea or breathing problems, and the optimal dose may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN

Contacts and locations

Locations

The Second Affiliated Hospital of Zhejiang University anesthesiology department
RECRUITING

Hanzhong, Zhejiang, 3100000, China

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