New painkiller could ease recovery after bone surgery
NCT ID NCT07353996
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a single injection of tegileridine fumarate, a new painkiller, for adults recovering from orthopedic surgeries like spinal fusion or knee replacement. Researchers aim to find the dose that works for 90% of patients without causing too many side effects. 180 participants will receive different doses to see which provides the best pain relief with the fewest problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tegileridine fumarate (a painkiller)
What this could lead to
If successful, this could establish a safe, effective single dose of tegileridine for managing pain after common orthopedic surgeries, improving recovery.
What could go wrong
This is a small, early-phase dose-finding study, not a large efficacy trial. The drug may cause side effects like nausea or breathing problems, and the optimal dose may not work for everyone.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE PAIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
The Second Affiliated Hospital of Zhejiang University anesthesiology department
RECRUITINGHanzhong, Zhejiang, 3100000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••