Shock wave device aims to smash heart artery calcium

NCT ID NCT06885177

Ongoing Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tests a new device that uses shock waves to break up calcium deposits in heart arteries before placing a stent. About 335 adults with coronary artery disease will receive this treatment at up to 55 US sites. The goal is to see if the device helps stents work better and reduces complications like heart attack or repeat procedures within 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Coronary Intravascular Lithotripsy (IVL) System
What this could lead to: If successful, this device could offer a safer, more effective way to treat heavily calcified coronary arteries, potentially reducing the need for repeat procedures and improving outcomes for patients with complex heart disease.
What could go wrong: This is an early-stage study with no control group, so results may not be definitive. The device may not work as well in all patients, and risks include heart attack, need for repeat procedures, or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary atherosclerosis coronary stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY CALCIFICATION CORONARY ARTERY DISEASE STENOTIC CORONARY LESION

Contacts and locations

Locations

Abbott Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
AdventHealth Orlando

Orlando, Florida, 32803, United States
AdventHealth Tampa

Tampa, Florida, 33613, United States
Arkansas Heart Hospital

Little Rock, Arkansas, 72211, United States
Ascension St. John Jane Phillips

Bartlesville, Oklahoma, 74006, United States
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
Baylor Scott & White Heart & Vascular Hospital

Dallas, Texas, 75226, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Brigham & Women's Hospital

Boston, Massachusetts, 02115, United States
Bryan Heart

Lincoln, Nebraska, 68506, United States
Carle Foundation Hospital

Urbana, Illinois, 61801, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Endeavor Health

Glenview, Illinois, 60201, United States
First Coast Cardiovascular Institute

Jacksonville, Florida, 32256, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
HonorHealth

Scottsdale, Arizona, 85258, United States
Jersey Shore University Medical Center

Neptune City, New Jersey, 07753, United States
Kaiser Permanente - San Francisco

San Francisco, California, 94118, United States
MedStar Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States
Montefiore Medical Center - Moses Division

The Bronx, New York, 10469, United States
Morristown Medical Center

Morristown, New Jersey, 07960, United States
Mt. Sinai Medical Center

Miami Beach, Florida, 33140, United States
North Shore University Hospital

Manhasset, New York, 11030, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Pinnacle Health System

Mechanicsburg, Pennsylvania, 17050, United States
Shannon Clinic

San Angelo, Texas, 76903, United States
Spartanburg Regional Medical Center

Spartanburg, South Carolina, 29303, United States
St. Francis Hospital

Roslyn, New York, 11576, United States
The Cardiac & Vascular Institute Research Foundation, LLC

Gainesville, Florida, 32605, United States
The Heart Hospital Baylor Plano

Plano, Texas, 75093, United States
UF Health Jacksonville

Jacksonville, Florida, 32209, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Louisville

Louisville, Kentucky, 40202, United States
University of South Florida

Tampa, Florida, 33606, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
University of Vermont Medical Center

Burlington, Vermont, 05401, United States
University of Washington Medical Center

Seattle, Washington, 98195, United States
Via Christi Regional Medical Center - St. Francis Campus

Wichita, Kansas, 67214, United States
Wellstar Kennestone Regional Medical Center

Marietta, Georgia, 30060, United States

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