Scientists test Lab-Made corneal implants to restore sight

NCT ID NCT04319848

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tests a new type of corneal graft made from lab-grown human cells. It is for people with mild to moderate corneal damage from conditions like Fuchs' dystrophy or after eye surgery. The goal is to see if the graft is safe and can improve vision. 30 participants are being enrolled in Singapore.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tissue-engineered corneal endothelial graft

What this could lead to

If successful, this could provide a new treatment option for corneal damage using lab-grown cells, potentially reducing the need for donor corneas.

What could go wrong

This is an early Phase 1 trial with only 30 participants, so safety and effectiveness are not yet proven. The graft may not work as expected or could cause complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bullous keratopathy corneal edema Fuchs' endothelial dystrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Singapore Eye Research Institute

    RECRUITING

    Singapore, Singapore

    Contact