Scientists test Lab-Made corneal implants to restore sight
NCT ID NCT04319848
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial tests a new type of corneal graft made from lab-grown human cells. It is for people with mild to moderate corneal damage from conditions like Fuchs' dystrophy or after eye surgery. The goal is to see if the graft is safe and can improve vision. 30 participants are being enrolled in Singapore.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tissue-engineered corneal endothelial graft
- What this could lead to
- If successful, this could provide a new treatment option for corneal damage using lab-grown cells, potentially reducing the need for donor corneas.
- What could go wrong
- This is an early Phase 1 trial with only 30 participants, so safety and effectiveness are not yet proven. The graft may not work as expected or could cause complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Singapore Eye Research Institute
RECRUITINGSingapore, Singapore
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- One shot to see clearly: cell therapy takes on corneal edema
- Cell injection could replace corneal transplants for blurry vision
- Built-In eye scanner could give surgeons a live 3D view during operations
- Eye surgery showdown: which cornea transplant is safer?
- Could a 15-minute dip in your own blood save your cornea transplant?
- First human trial of Lab-Grown corneal implant launches