Could a gentle brain zapper curb opioid cravings?
NCT ID NCT06432465
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive brain stimulation technique called tDCS can reduce opioid cravings and prevent relapse. Researchers will compare active stimulation to a sham (fake) version in 100 adults with opioid use disorder who recently started medication like buprenorphine or methadone. The goal is to see if targeting the prefrontal cortex can strengthen self-control and lower the chance of returning to opioid use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could offer a non-drug way to help people with opioid use disorder resist cravings and avoid relapse.
What could go wrong
This is a mid-stage trial with 100 participants, so results may not apply to everyone. The stimulation may cause discomfort or fail to reduce relapse rates.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Butler Hospital
RECRUITINGProvidence, Rhode Island, 02906, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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