Zapping the brain to boost motivation in seniors

NCT ID NCT05232877

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a gentle electrical brain stimulation technique called tDCS, combined with cognitive training on a tablet, can reduce apathy in older adults with mild cognitive impairment. Apathy is a lack of motivation and interest that can affect daily life. The trial involves 27 participants aged 65 and older who will receive either real tDCS plus training or a sham (fake) version over 12 sessions in 4 weeks. The goal is to see if this combination can improve emotional engagement, initiative, and interest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS) combined with cognitive training

What this could lead to

If it works, this could offer a non-drug way to ease apathy in older adults with mild cognitive problems, improving motivation and daily function.

What could go wrong

This is a small, early-phase study with only 27 participants, so results may not apply widely. The effect of tDCS can be subtle, and the sham group may also improve.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for APATHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cognitive disorder Lethargy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Memoire Ressources et Recherche, CHU de Nice

    Nice, 06000, France