Engineered immune cells take on Hard-to-Treat breast cancer

NCT ID NCT05989828

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 15 times

Summary

This early-stage trial tests a personalized cell therapy for people with advanced triple negative breast cancer that has stopped responding to standard treatments. Researchers take a patient's own immune cells, modify them in the lab to recognize a protein called NY-ESO-1 found on cancer cells, and return them to the body to attack the tumor. The study aims to find the safest dose and monitor side effects in up to 20 participants.

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Contacts and locations

Locations

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

Explore the condition pages connected to this study.