Can Computer-Controlled sedation reduce breathing risks during spine surgery?
NCT ID NCT07745348
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study compares two ways of giving sedation during kyphoplasty, a procedure to treat spinal fractures, performed while the patient lies face down. One method uses a computer-controlled infusion of the sedative propofol, while the other relies on manual dosing. The main goal is to see which approach leads to fewer episodes of low oxygen or pauses in breathing. The trial also looks at how quickly patients wake up and recover, as well as satisfaction from both patients and surgeons.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Target-controlled infusion (TCI) of propofol compared with manually administered total intravenous anesthesia (TIVA)
- What this could lead to
- If TCI proves safer, it could become the preferred sedation method for spine surgeries, reducing breathing complications and improving recovery.
- What could go wrong
- This is a small, single-center study, so results may not apply broadly. Individual responses to sedation vary, and the study does not guarantee a clear advantage for TCI.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seniyye Ülgen Zengin
Istanbul, Maltepe, 34854, Turkey (Türkiye)
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