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Which anesthesia model keeps patients more stable during spine surgery?

NCT ID NCT07586189

Knowledge-focused Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 19, 2026 · Updated 5 times

Summary

This study compares two computer-controlled methods (Eleveld and Schnider) for giving propofol anesthesia during spinal fusion surgery. Fifty adults will be randomly assigned to one method, and researchers will track blood pressure, heart rate, and brain activity to see which model provides more stable sedation. The goal is to find which approach leads to fewer drops in blood pressure or other complications during the start of anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propofol
What this could lead to
If successful, this could help doctors choose the best anesthesia model for safer, more stable sedation during spinal surgery.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply to all patients or surgeries. It compares existing methods, not a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients scheduled for elective spinal surgery under general anesthesia at the Neurosurgery Department of Istanbul University, Istanbul Faculty of Medicine. Eligible patients will be 18 years of age or older and will provide written informed consent before enrollment. Patients with uncontrolled hypertension, uncontrolled diabetes mellitus, those younger than 18 years of age, and patients who do not provide consent will be excluded from the study. Eligible participants will be randomized to receive propofol target-controlled infusion using either the Schnider or Eleveld model for anesthetic induction. Hemodynamic parameters and bispectral index values will be evaluated during the first 10 minutes of the induction period.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for elective spinal surgery under general anesthesia * Patients who will undergo surgery at the Neurosurgery Department of Istanbul University, Istanbul Faculty of Medicine * Patients aged 18 years or older * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Patients with uncontrolled hypertension * Patients with uncontrolled diabetes mellitus * Patients younger than 18 years of age * Patients who do not provide informed consent to participate in the study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia depth monitoring Bis-eeg Spinal (fusion) surgery Target controlled infusion of propofol Total intravenous anesthesia

How to take part

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  1. The places running it

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  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Istanbul University

    RECRUITING

    Istanbul, Turkey (Türkiye)

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