Could a 1-Month pill course stop TB in schools?

NCT ID NCT06022146

Recruiting now Disease control Sponsor: Huashan Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study tests whether a 4-week course of two TB drugs works as well as the standard 3-month course to prevent active TB in students and staff who have been exposed. About 3,520 people from schools will take either the short or standard regimen. The goal is to see if the shorter option is easier to complete and just as effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: isoniazid and rifapentine
What this could lead to: If successful, this could offer a shorter, easier TB prevention option for teens and young adults, potentially increasing the number of people who complete treatment.
What could go wrong: This is a large phase 3 trial, but the shorter regimen may still cause side effects or be less effective than the standard 3-month course. Results may not apply outside school settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection tuberculosis active tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LATENT TUBERCULOSIS TUBERCULOSIS

Contacts and locations

Locations

3rd People's Hospital of Bijie
RECRUITING

Bijie, China
Chinese Medicine Hospital of Qingzhen
RECRUITING

Guiyang, China
Dalian Public Health Clinical Center
RECRUITING

Dalian, Liaoning, China
First People's Hospital of Fuquan
RECRUITING

Qiannan, Guizhou, China
First People's Hospital of Kaili
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
Guiyang Public Health Treatment Center
RECRUITING

Guiyang, Guizhou, China
Guizhou Aerospace Hospital
RECRUITING

Zunyi, Guizhou, China
Huashan Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Liuzhi Special District
RECRUITING

Liupanshui, Guizhou, China
People's Hospital of Baiyun District
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Bozhou District
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Cengong
RECRUITING

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China
People's Hospital of Changshun
RECRUITING

Qiannan, China
People's Hospital of Chishui
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Congjiang
RECRUITING

Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China
People's Hospital of Dafang Town
RECRUITING

Bijie, China
People's Hospital of Danzhai
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Daozhen Klau and Hmong autonomous county
RECRUITING

Daozhen Klau and Hmong Autonomous County in Zun'yi, Guizhou, China
People's Hospital of Fenggang
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Guanling
RECRUITING

Anshun, Guizhou, China
People's Hospital of Hezhang
RECRUITING

Bijie, Guizhou, China
People's Hospital of Honghuagang District
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Huangping
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Huaxi District
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Jianhe
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Jinping
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Kaiyang
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Leishan
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Libo
RECRUITING

Qiannan, Guizhou, China
People's Hospital of Liping
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Luodian
RECRUITING

Qiannan, Guizhou, China
People's Hospital of Majiang
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, China
People's Hospital of Meitan
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Nayong
RECRUITING

Bijie, China
People's Hospital of Panzhou
RECRUITING

Liupanshui, Guizhou, China
People's Hospital of Pingba District
RECRUITING

Anshun, Guizhou, China
People's Hospital of Puding
RECRUITING

Anshun, Guizhou, China
People's Hospital of Qianxi
RECRUITING

Bijie, Guizhou, China
People's Hospital of Qianxi
RECRUITING

Bijie, Guizhou, China
People's Hospital of Renhuai
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Rongjiang
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Sansui
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Shibing
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Shuicheng District, Liupanshui City
RECRUITING

Liupanshui, Guizhou, China
People's Hospital of Suiyang
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Taijiang
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, China
People's Hospital of Tianzhu
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Tongzi
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Wanshan District
RECRUITING

Tongren, Guizhou, China
People's Hospital of Weining
RECRUITING

Bijie, Guizhou, China
People's Hospital of Wuchuan Klau and Hmong autonomous county
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Wudang District
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Xifeng
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Xishui
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Xiuwen
RECRUITING

Guiyang, Guizhou, China
People's Hospital of Xixiu District
RECRUITING

Anshun, Guizhou, China
People's Hospital of Yuqing
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Zhengan
RECRUITING

Zunyi, Guizhou, China
People's Hospital of Zhenning
RECRUITING

Anshun, Guizhou, China
People's Hospital of Zhenyuan
RECRUITING

Qiandongnan Miao and Dong Autonomous Region, Guizhou, China
People's Hospital of Zhijin
RECRUITING

Bijie, Guizhou, China
People's Hospital of Ziyun
RECRUITING

Anshun, Guiyang, China
Second People's Hospital of Liupanshui City
RECRUITING

Liupanshui, Guizhou, China
Third People's Hospital of Liupanshui
RECRUITING

Liupanshui, Guizhou, China
Zunyi Infectious Disease Hospital
RECRUITING

Zunyi, Guizhou, China
Zunyi Infectious Disease Hospital
RECRUITING

Zunyi, Guizhou, China

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