Could a 1-Month pill course stop TB in schools?

NCT ID NCT06022146

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 4-week course of two TB drugs works as well as the standard 3-month course to prevent active TB in students and staff who have been exposed. About 3,520 people from schools will take either the short or standard regimen. The goal is to see if the shorter option is easier to complete and just as effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

isoniazid and rifapentine

What this could lead to

If successful, this could offer a shorter, easier TB prevention option for teens and young adults, potentially increasing the number of people who complete treatment.

What could go wrong

This is a large phase 3 trial, but the shorter regimen may still cause side effects or be less effective than the standard 3-month course. Results may not apply outside school settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection tuberculosis active tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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Locations

  • 3rd People's Hospital of Bijie

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    Bijie, China

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  • Chinese Medicine Hospital of Qingzhen

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    Guiyang, China

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  • Dalian Public Health Clinical Center

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    Dalian, Liaoning, China

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  • First People's Hospital of Kaili

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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  • Guizhou Aerospace Hospital

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    Zunyi, Guizhou, China

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  • Huashan Hospital

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    Shanghai, Shanghai Municipality, 200040, China

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  • Liuzhi Special District

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    Liupanshui, Guizhou, China

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  • People's Hospital of Bozhou District

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    Zunyi, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

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  • People's Hospital of Chishui

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    Zunyi, Guizhou, China

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  • People's Hospital of Congjiang

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    Qiandongnan Miao and Dong Autonomous Prefecture, Guizhou, China

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  • People's Hospital of Dafang Town

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    Bijie, China

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  • People's Hospital of Danzhai

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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  • People's Hospital of Daozhen Klau and Hmong autonomous county

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    Daozhen Klau and Hmong Autonomous County in Zun'yi, Guizhou, China

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  • People's Hospital of Fenggang

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    Zunyi, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, China

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    Zunyi, Guizhou, China

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    Bijie, China

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    Liupanshui, Guizhou, China

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    Bijie, Guizhou, China

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    Zunyi, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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  • People's Hospital of Shuicheng District, Liupanshui City

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    Liupanshui, Guizhou, China

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  • People's Hospital of Suiyang

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    Zunyi, Guizhou, China

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  • People's Hospital of Taijiang

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    Qiandongnan Miao and Dong Autonomous Region, China

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  • People's Hospital of Tianzhu

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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  • People's Hospital of Tongzi

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    Zunyi, Guizhou, China

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  • People's Hospital of Weining

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    Bijie, Guizhou, China

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  • People's Hospital of Wuchuan Klau and Hmong autonomous county

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    Zunyi, Guizhou, China

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  • People's Hospital of Xishui

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    Zunyi, Guizhou, China

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  • People's Hospital of Yuqing

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    Zunyi, Guizhou, China

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  • People's Hospital of Zhengan

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    Zunyi, Guizhou, China

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  • People's Hospital of Zhenyuan

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    Qiandongnan Miao and Dong Autonomous Region, Guizhou, China

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    Bijie, Guizhou, China

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    Bijie, Guizhou, China

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  • Poeple's Hospital of Leishan

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  • Second People's Hospital of Liupanshui City

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  • Zunyi Infectious Disease Hospital

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    Zunyi, Guizhou, China

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