Can a vaccine boost TB treatment? new trial aims to find out

NCT ID NCT06205589

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental vaccine called ID93 + GLA-SE in 1500 people with drug-susceptible pulmonary TB. Participants receive the vaccine or a placebo alongside their regular TB treatment. Researchers want to see if the vaccine can improve immune responses and reduce poor outcomes like treatment failure or TB coming back. It is the first time this vaccine is tested in people living with HIV.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ID93 + GLA-SE vaccine
What this could lead to
If successful, this vaccine could become an add-on to standard TB treatment, reducing treatment failure and TB recurrence.
What could go wrong
This is a Phase 2 trial, so it is still early. The vaccine may not prove effective or safe in larger populations, and results may not apply to all TB patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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