Could a new skin test better detect TB in seniors?

NCT ID NCT05899179

Completed Diagnosis Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new skin test called EC to see if it can accurately diagnose tuberculosis (TB) infection in adults aged 65 and older. Researchers compared EC with a standard TB skin test (TB-PPD) and a blood test (T-SPOT) in 780 participants, including TB patients and healthy volunteers. The goal was to see how well EC detects infection and whether it causes any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Recombinant Mycobacterium Tuberculosis Fusion Protein (EC) injection
What this could lead to: If successful, this could provide a more accurate skin test for detecting tuberculosis infection in older adults, improving diagnosis and treatment.
What could go wrong: This is a completed phase 3 trial, but results are not yet published. The test may not be significantly better than existing methods, and skin reactions can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

latent tuberculosis infection tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LATENT TUBERCULOSIS INFECTION

Contacts and locations

Locations

Anhui Chest Hospital

Hefei, Anhui, China
Changsha Central Hospital

Changsha, Hunan, China
Guangzhou Municipal Hospital of Chest Medicine

Guangzhou, Guangdong, China
LiuZhou People's Hospital

Liuzhou, Guangxi, China
The First Affiliated Hospital of Bengbu Medical University

Bengbu, Anhui, China
The Third People's Hospital Of Shenzhen

Shenzhen, Guangdong, China
Wuhan Institute for Tuberculosis Control

Wuhan, China
Wuxi NO.5 People's Hospital

Wuxi, Jiangsu, China

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