New TB detection methods could save thousands of lives in africa
NCT ID NCT06437184
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find more tuberculosis (TB) cases by improving diagnostic tools already available in local health clinics. About 1,584 adults with TB symptoms in Guinea-Bissau and Ethiopia will be randomly assigned to either standard care or an enhanced testing approach that includes better sputum collection, chest X-rays with computer help, and additional tests. The goal is to see if these improvements lead to more people being diagnosed and treated quickly, which could reduce TB spread in communities.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,584 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2024
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 120 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ≥15 years old * presumed TB with cough, sputum production, and/or weight loss of any duration Exclusion Criteria: * TB treatment within the past year. * Cerebral disturbances impairing the ability to give informed consent or follow the treatment regime.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gondar University
RECRUITINGGonder, Ethiopia
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Projecto Saude de Bandim
RECRUITINGBissau, Guinea-Bissau
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Other studies related to the condition(s) this trial covers.
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- Could a new TB drug interfere with birth control pills?