Promising combo for rare sarcoma stalls as trial ends early
NCT ID NCT04204941
First seen Jan 09, 2026 · Last updated May 16, 2026 · Updated 20 times
Summary
This study tested a new drug called tazemetostat combined with standard chemotherapy (doxorubicin) for people with advanced epithelioid sarcoma, a rare cancer of connective tissues. The goal was to see if the combination was safe and could help people live longer without their cancer worsening. The trial was stopped early, so we have limited information on how well it worked.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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Dana Farber Cancer Insititute
Boston, Massachusetts, 02215, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Fred Hutchinson Research Center
Seattle, Washington, 98109, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02214, United States
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Mayo Clinic-Jacksonville
Jacksonville, Florida, 32224, United States
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McGill University Faculty of Medicine - Royal Victoria Hospital
Montreal, Quebec, H4A 3J1, Canada
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National Taiwan University Hospital
Taipei, 100, Taiwan
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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Royal Marsden Foundation Trust
London, SW3 6JJ, United Kingdom
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Sarah Cannon Research Institute at HealthONE
Denver, Colorado, 80218, United States
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Sarah Cannon and HCA Research Institute
Nashville, Tennessee, 37203, United States
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Sarcoma Oncology Research Center
Santa Monica, California, 90403, United States
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The Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
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University of Colorado Hospital - Anschutz Cancer Pavilion
Aurora, Colorado, 80045, United States
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University of Michigan Medical Center
Ann Arbor, Michigan, 48109, United States
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University of Pittsburgh Medical Center - Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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