Ear-Zapping device could offer Drug-Free relief for stubborn constipation

NCT ID NCT07344402

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether a small device that stimulates a nerve in the ear (taVNS) can help people with constipation that hasn't improved with standard treatments. One hundred adults will be randomly assigned to receive either active or sham stimulation twice daily for 20 days. Researchers will track bowel movements and side effects to see if the device provides real relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcutaneous auricular vagus nerve stimulation (taVNS) device
What this could lead to
If it works, this could offer a drug-free, non-invasive option for people with hard-to-treat constipation.
What could go wrong
This is an early-stage trial with only 100 participants, and the sham group may also show some benefit. The effect may be modest or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xijing Hospital

    RECRUITING

    Xi'an, China

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Other studies related to the condition(s) this trial covers.