New study aims to cut unnecessary pacemakers after TAVI

NCT ID NCT05308888

First seen Jun 11, 2026 · Last updated Jun 22, 2026 · Updated 2 times

Summary

This study looks at whether inflammation after a minimally invasive heart valve replacement (TAVI) can cause dangerous heart rhythm problems. Researchers will use a special PET scan to measure inflammation in the heart's electrical pathways. The goal is to better predict which patients truly need a pacemaker, avoiding unnecessary implants and their risks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Brest

    RECRUITING

    Brest, 29609, France

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-FDG (a radioactive tracer used in PET scans)

What this could lead to

If successful, this could help doctors predict which patients truly need a pacemaker after TAVI, avoiding unnecessary implants and their complications.

What could go wrong

This is an early exploratory study with only 100 participants, so results may not apply to everyone. It uses imaging to observe inflammation, not to test a new treatment.

Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.