Single dose of radiation during lumpectomy may control early breast cancer
NCT ID NCT01570998
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests giving a single dose of radiation directly to the tumor site during breast-conserving surgery for early-stage breast cancer. The goal is to see if this one-time treatment works as well as standard radiation therapy that requires multiple visits. Over 1,200 participants are being followed for up to 5 years to check for cancer return, side effects, and survival.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, 94704, United States
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Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311, United States
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Cleveland Clinic
Fort Lauderdale, Florida, 33308, United States
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Columbia University/Herbert Irving Cancer Center
New York, New York, 10032, United States
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Community Cancer Center South
Indianapolis, Indiana, 46227, United States
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Community Hospital at Dobbs Ferry
Dobbs Ferry, New York, 10522, United States
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Cornell University
Ithaca, New York, 14850-2488, United States
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Dignity Health - California Hospital Medical Center
Los Angeles, California, 90015, United States
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Greenwich Hospital
Greenwich, Connecticut, 06830, United States
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Holy Cross Hospital
Fort Lauderdale, Florida, 33308, United States
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Inova Fairfax Hospital Cancer Center
Fairfax, Virginia, 22031, United States
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John Muir Medical Center-Walnut Creek
Walnut Creek, California, 94598, United States
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Lahey Hospital and Medical Center
Burlington, Massachusetts, 01805, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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Marie Yeager Cancer Center, Spectrum Health Lakeland
Saint Joseph, Michigan, 49085, United States
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MedStar Georgetown University Hospital
Washington D.C., District of Columbia, 20007, United States
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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Memorial Health University Medical Center
Savannah, Georgia, 31404, United States
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Mercy Medical Center
Baltimore, Maryland, 21202, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Saint Luke's Hospital-Anderson Campus
Easton, Pennsylvania, 18045, United States
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Sentara Port Warwick
Newport News, Virginia, 23606, United States
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University of California, Irvine
Irvine, California, 92617, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
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Vassar Brothers Medical Center
Poughkeepsie, New York, 12601, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a one-week radiation zap be just as good as three weeks for early breast cancer?
- New chemo combo aims to shrink aggressive breast cancer before surgery
- One-Time radiation boost during breast surgery shows promise in Early-Stage cancer trial