New radiation drug shows promise for kids with incurable brain tumors

NCT ID NCT05610891

First seen Apr 01, 2026 · Last updated Jun 10, 2026 · Updated 12 times

Summary

This study tests a new drug called CLR 131, a type of targeted radiotherapy, in children, teens, and young adults (ages 10-25) with a hard-to-treat brain cancer called high-grade glioma that has come back or not responded to treatment. The main goals are to find the safest dose and see if it can shrink tumors or slow the cancer's growth. About 50 participants will receive one of two dose levels, and doctors will monitor side effects and use MRI scans to measure response.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIGH GRADE GLIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Stanford University

    Palo Alto, California, 94304, United States

  • Texas Children's Cancer Center, Baylor College of Medicine

    Houston, Texas, 77030, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Wisconsin, Carbone Cancer Center

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.