Smart radiation seeks out lung cancer cells in new trial

NCT ID NCT06228482

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial is testing a pair of radioactive drugs designed to find and attack non-small cell lung cancer that has spread. First, a scanning drug highlights tumors. Then, a therapeutic drug delivers radiation directly to those tumors. The study will enroll 40 adults whose cancer has worsened despite standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Radioactive drugs [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G
What this could lead to
If it works, this could offer a new targeted treatment option for people with advanced lung cancer that has spread.
What could go wrong
This is an early Phase 1 trial with only 40 people, so it's too soon to know if it works. The treatment involves radiation, which can cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of California Davis Comprehensive Cancer Center

    RECRUITING

    Sacramento, California, 95817, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.