New gel aims to stop chemo side effect that makes hands hurt

NCT ID NCT07457671

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a gel called TAR-0520 to see if it can prevent hand-foot syndrome, a painful skin reaction caused by the chemotherapy drug capecitabine. About 25 people with breast or colorectal cancer will apply the gel to their hands twice daily for 12 weeks. Their feet will not be treated and will serve as a comparison. The goal is to check if the gel is safe and reduces the severity of hand-foot syndrome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TAR-0520 gel

What this could lead to

If it works, this could point toward a way to prevent painful hand-foot syndrome in cancer patients taking capecitabine, improving their quality of life.

What could go wrong

This is a small, early-phase study with only 25 people. It may not show clear benefit, and the gel could cause local skin reactions or not reduce symptoms enough to matter.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer colorectal cancer hand-foot syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Instiut Paoli-Calmettes

    Marseille, 13009, France

    Contact Phone: •••-•••-••••